CJC-1295 No DAC is a 30-amino-acid growth hormone releasing hormone (GHRH) analog with a short biological half-life, producing pulsatile GH release in research models. Ipamorelin is a pentapeptide ghrelin-receptor agonist (GHS) that selectively stimulates GH secretion.
HHB is a nine-part blend of B-vitamins and lipotropic nutrients studied for their roles in hair, skin and nail biology, supplied as a ready-to-use sterile solution in a 10 mL vial at 150.3 mg per mL. It arrives already in solution, so there is no reconstitution step. Each milliliter carries the full 150.3 mg load, and the sealed vial holds 1,503 mg across the nine ingredients, including 1 mg of biotin. PrymaLab supplies HHB for laboratory research use only.
Every vial is the same nine-ingredient formula. The amounts below are per milliliter and per full 10 mL vial.
Ingredient Per 10 mL vial
Niacinamide (B3) 50 mg, Thiamine HCl (B1) 50 mg, Pantothenic acid (B5) 25 mg, Choline 10 mg, Inositol 10 mg, Niacin (B3) 5 mg, Biotin (B7) 100 mcg, Folic acid (B9) 100 mcg, Riboflavin (B2) 100 mcg.
Specification Detail
Ready-to-use sterile solution. Shelf life, sealed 12 to 24 months (see storage). Shelf life, punctured 30 days refrigerated at 2 to 8°C in the box.
Niacinamide is the B3 form that does not cause the flush nicotinic acid can. In cells it converts to nicotinamide adenine dinucleotide (NAD+), a coenzyme used across hundreds of reactions. For the scalp its job is blood flow: wider vessels move more oxygen and nutrients to follicles and clear waste around them. Niacinamide also raises expression of keratin genes, the protein behind both hair shafts and nail plates, while promoting overall skin health. At 50 mg per mL it sits well above the standard adequate intake for dietary B3.
Thiamine HCl is the stable, water-soluble form of B1 and an essential nutrient that acts as a cofactor for pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase, two enzymes that turn glucose into ATP. Hair-matrix cells divide every 24 to 48 hours during the growth phase, one of the fastest turnovers in the body, and that pace runs on ATP. Thiamine also feeds the pentose phosphate pathway, which makes the NADPH follicles use against oxidative stress. The hydrochloride form dissolves cleanly and keeps well in the vial.
Pantothenic acid (B5), often found in supplements as calcium pantothenate, is the precursor to coenzyme A, which cells use to build the ceramide, fatty acids, and amino acids that become keratin.
Low B5 slows keratin output, and hair and nails grow in weaker and more brittle. B5 also feeds adrenal hormone production, the stress axis tied to telogen effluvium, the shedding pattern that follows a stressful stretch of months. The 25 mg per mL keeps a steady supply reaching the follicle.
Choline is one of two lipotropic nutrients here. It builds phosphatidylcholine, the main phospholipid in every follicle-cell membrane, and acetylcholine, which helps set blood-vessel tone in the scalp. Choline also carries methyl groups through the methylation cycle that rapidly dividing follicle and nail-matrix cells use to copy DNA accurately. At 10 mg it works alongside the B-vitamins rather than on its own.
Inositol is the second lipotropic nutrient. As phosphatidylinositol it becomes the second messengers IP3 and DAG, the signals a cell reads when growth factors and hormones tell a follicle what to do. Its lipotropic action, paired with choline, keeps sebum production balanced so the scalp is neither dry nor greasy. Inositol also buffers oxidative stress in tissue that turns over as fast as a hair follicle, and is studied for nail-plate integrity by a systemic route that topical cuticle oils do not take.
Niacin (nicotinic acid) is the flushing B3 form, kept low here at 5 mg on purpose. It triggers a prostaglandin release that widens blood vessels, adding to the circulation niacinamide already improves, while the small amount keeps the flush response reported in human niacin studies mild. Like niacinamide it tops up the NAD+ pool that follicle energy and DNA repair depend on.
Biotin (B7) is the vitamin most people already connect with hair and nails. It is the cofactor for five carboxylase enzymes in fatty-acid and amino-acid metabolism, the raw materials for keratin, and it raises expression of keratin genes directly. A study in the Journal of the American Academy of Dermatology reported that 2.5 mg of daily biotin increased nail-plate thickness by 25% and cut splitting in people with brittle nail syndrome. The 100 mcg per mL here is above the 30 microgram daily adequate intake cited for adults, and parenteral delivery in the literature avoids the gut losses measured with oral biotin and biotin-rich foods. Biotin is often discussed for hair growth, though the strongest human data is for nail growth rather than hair.
Folic acid (B9) carries the one-carbon units cells use to make the purines and thymidine in new DNA, so tissue that divides constantly, like the hair matrix and nail bed, depends on a steady supply. Folate also builds red blood cells, and low folate causes a megaloblastic anemia that, much like iron deficiency, starves follicles of oxygen.
At 100 mcg per mL it keeps DNA synthesis supplied at the follicle.
Riboflavin (B2) becomes FMN and FAD, the electron carriers in the chain that makes most of a cell’s ATP. It also regenerates glutathione, the antioxidant follicles lean on under oxidative load, and it activates B6 and helps process folate and niacin, so a B2 shortfall drags the others down with it. Riboflavin is also why urine turns bright yellow in B-complex supplementation studies: that color is excess B2 leaving the body.
The B-complex vitamins share pathways, so a shortfall in one caps the rest. Riboflavin activates B6 and processes folate and niacin; thiamine and niacin both feed energy metabolism. Supplying them together keeps any single vitamin from becoming the limiting step. Choline and inositol pair for a stronger lipotropic effect than either gives alone. The two B3 forms split the work on circulation, niacinamide without flushing and niacin with mild vasodilation. Biotin and pantothenic acid cover the keratin-building side, while the rest supply the energy and DNA replication that keratin production runs on. Because it is one solution, all nine are present together in a fixed ratio.
The research interest in B-vitamin blends comes from deficiency work. Lower biotin, riboflavin, folate and B12 show up in people with diffuse hair loss and brittle nails, and groups who absorb less from food (older adults, people on acid-reducing medication, vegans and vegetarians) run low more often. None of that literature studies a hair and nail injection as a product, and no B-vitamin acts on genetically driven hair loss. The nine actives in HHB are B vitamins, choline and inositol.
MOTS-C is a short peptide encoded with the 12S ribosomal RNA gene of mitochondrial DNA. It was first characterized in 2015 by Changhan Lee, Pinchas Cohen, and colleagues at the University of Southern California, who showed that the peptide acts as a hormone-like signal regulating whole-body metabolism.
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme present in every living cell. It shuttles electrons between metabolic reactions by cycling between its oxidized form, NAD+, and its reduced form, NADH, which places it at the center of glycolysis, the citric acid cycle, and oxidative phosphorylation.
The Wolverine Blend — combines two of the most extensively studied peptides in preclinical science at a fixed 1:1 ratio.
BPC-157 (Body Protection Compound-157, CAS 137525-51-8) is a stable 15-amino-acid pentadecapeptide derived from a protective protein found in human gastric juice.
TB-500 (CAS 77591-33-4) is a synthetic analog of the active region of Thymosin Beta-4, a 43-amino-acid protein abundant in platelets.
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